Progestrone is known as the ‘pro-gestational’ hormone in that it essentially gives life. Estrogen has inaproppriatley been named the “female hormone” but considering men have estrogen one could argue progesterone should have that moniker.

Natural Progesterone has many benefits such as combating anxiety, lowering cortisol, improving thyroid secretion, bone growth, reversing many aging signs etc. Most importantly it was known in the 40’s to combat the harmful effects of estrogen.

However, a doctrine quickly arose that natural progesterone and other steroids were destroyed in the stomach. This was not true but it was enough momentum to stop inexpensive tablets of progesterone and be replaced with synthetic progestins. Doctors who still wanted to use natural progesterone had to use an injectable form. This wasn’t as patient friendly and hard to store due to solubility.

Natural progesterone should contain vitamin E and not just tocopheral acetate. It will lose about half it’s effect if in a tocopheral which is like an incomplete version of vitamin E.

Olive oil works well when applied topically and ideally on membranes. A 10% solution seems to be the appropriate dosage with higher dosages causing an anesthetic effect and a drunkenness.

There are some confusion with terminology. Progestin and progesterone tend to get interchanged as the same thing. They are not!! Progestin is the synthetic version of progesterone. It will not have the same affect as bio-identical or natural progesterone. Doctors commonly get confused with this one too.

Progesterone is a basic hormone that aids with your resistance to stress. The adrenal glands use it to produce their antistress hormones. When there is enough progesterone the adrenals don’t have to release harmful cortisol. When progesterone is low, we produce too much cortisol, and excessive cortisol causes osteoporosis, aging of the skin, damage to brain cells, and the accumulation of fat, especially on the back and abdomen.

“Experiments have shown that progesterone relieves anxiety, improves memory, protects brain cells, and even prevents epileptic seizures. It promotes respiration, and has been used to correct emphysema In the circulatory system, it prevents bulging veins by increasing the tone of blood vessels, and improves the efficiency of the heart. It reverses many of the signs of aging in the skin, and promotes healthy bone growth. It can relieve many types of arthritis, and helps a variety of immunological problems.” Ray Peat

FOR PMS: The normal pattern of progesterone secretion during the month is for the ovaries to produce a large amount in the second two weeks of the menstrual cycle. That is typically day 14 -28 in the cycle and beginning at ovulation and ending at menstruation. Production of progesterone is little for the following two weeks. An average female produces about 30 milligrams daily during the second two weeks.

Taking natural progesterone orally or topically from day 14-28 would be the best approach. Having 3-4 drops a couple times a day can be enough to bring progesterone levels up. Listen to your symptoms. Since an essential mechanism of progesterone’s action involves its opposition to estrogen, smaller amounts are effective when estrogen production is low. If estrogen is extremely high, even large supplements of progesterone may be futile. Excess estrogen then needs a holistic approach by improving the diet, correcting a thyroid deficiency, helping elimination, and lowering polyunsaturated fats. Anything that lowers overall physical and mental stress will help.

PERIMENOPAUSAL: The symptoms and body changes leading up to menopause are associated with decreasing production of progesterone. This is also when estrogen may be at a lifetime high contrary to popular belief. The cyclic use of progesterone, two weeks on, two weeks off, will often keep the normal menstrual cycle going. Three to four drops, providing ten or twelve milligrams of progesterone, is typical for a day. Some women do prefer to repeat that amount. Progesterone is always more effective when the diet contains adequate protein, and when there isn’t an excessive amount of unsaturated fat in the diet.

POSTMENOPAUSAL: Some women continue the cyclic use of progesterone after menopause, because the pituitary gland and brain may continue to cycle long after menstruation has stopped. Progesterone is an important regulator of pituitary and brain function. The cycling pituitary affects the adrenal glands and other organs, and progesterone tends to protect against the unopposed actions of prolactin, cortisol, and adrenal hormones. Some women prefer to use progesterone without interruption after menopause, for its protective antistress effects. A person with higher body fat may need more progesterone to combat the estrogen. Estrogen tends to get stored in fat. Adequate protein in the diet and good thyroid function help the body to produce its own progesterone; even if the ovaries have been removed. Progesterone will continue to be produced in the brain and adrenals.


Supplementing Natural progesterone.

 Progesterone is very safe to take. It has none of the harmful side effects of other hormones (except for alteration of the menstrual cycle if it is taken at the wrong time of month). You want to use a sufficient quantity to make the symptoms disappear, and to time its use so that menstrual cycles are not disrupted. This normally means using it only between ovulation and menstruation unless symptoms are sufficiently serious that a missed period is not important.

To avoid unexpected anesthesia, the correct dose should be determined by taking about 10 mg. at a time and allowing it to spread into the membranes of the mouth, and repeating the dose after 10 minutes until the symptoms are controlled.

An excessive estrogen to progesterone ratio is more involved in producing or aggravating symptoms more than either a simple excess of estrogen or a deficiency of progesterone. Even this ratio is influenced by other factors, including age, diet, other steroids, thyroid, and other hormones.

Excess stress (which can block progesterone synthesis and elevate estrogen) may bring on symptoms in someone who never had them. Getting plenty of sunlight, or next best option, red light therapy may relieve the symptoms of a chronic sufferer. Lack of sunshine in winter is a powerful stressor and cause lower production of progesterone in women, and testosterone in men. Toxins can produce similar symptoms, as can nutritional deficiencies. A very common cause of an estrogen excess is a dietary protein deficiency.The liver simply cannot detoxify estrogen when it is under-nourished.

With a daily intake of protein (at least 100 grams per day) the dose of progesterone can be reduced each month. Using thyroid will usually reduce the amount of progesterone needed. Some woman won’t feel any effect even from 100 mg. of progesterone. This suggests that they need to use thyroid and diet, to normalize their estrogen, prolactin, and cortisol.

Progesterone stimulates the ovaries and adrenals to produce progesterone. It also activates the thyroid, so one dose can sometimes have prolonged effects. It shouldn’t be necessary to keep using progesterone indefinitely, unless the ovaries have been removed. In slender post-menopausal women, 10 mg. per day is usually enough to prevent progesterone deficiency symptoms.

The most effective way to take progesterone is with vitamin E orally and a few drops on lips or tongue or rubbed into the gums.These are thin membranes and it is absorbed quickly. Vitamin E allows it to be absorbed through the walls of the stomach and intestines. This allows it to circulate to all the organs before being processed by the liver.

Please share with someone who may benefit from this information. Important info that many don’t know about.

Further recommended reading:

Progesterone Summaries

Progesterone Deceptions

Progesterone , Pregnenolone, DHEA

Progesterone, not Estrogen is the coronary protection factor for women

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